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Scientific interest in L-carnitine as a performance enhancement and weight loss tool came to an end when it became apparent that L-carnitine feeding does not alter fuel metabolism during exercise or, more importantly impact upon the muscle carnitine pool in humans

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For instance, Lu et al

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These results suggest that NINJ1 interacts with xCT under basal conditions, potentially regulating its activity

The fact that the diphenolic substrates are able to cope better with the double mutation than the monophenolic substrates further indicates interference with the deprotonation step as it was proposed that diphenols do not require prior deprotonation 61