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However, DAMPs-mediated signalling can also generate detrimental effects, particularly when a massive release of pro-inflammatory DAMPs from dying cells causes more cells to die: a situation that strongly contributes to the CD4+ T cell depletion in patients infected with HIV-1 (63, 64), reviewed in (65)

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Novel a-ring chalcone derivatives of oleanolic and ursolic amides with anti-proliferative effect mediated through ROS-triggered apoptosis

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