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Ferroptosis in the kidney of diabetic models Prolonged high blood sugar can damage the glomeruli and renal tubules, gradually leading to impaired kidney function, known as diabetic nephropathy

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Furthermore, many oncological drugs are associated with hypokalemia: cisplatin, ifosfamide, anti-EGFR agents, mTOR inhibitors, eribulin, and abiraterone (333)

The predominant subset was undifferentiated phenotype with dysregulated respiratory electron transport, suggesting that disruptions in both metabolism and mitochondrial function are involved