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While our objective was to determine the rates of hepatotoxicity for the 2 routes, the optimal meta-analysis would compare oral and IV administration

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doi:10.1002/bip.21416

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PMCID: PMC8002905

However, their dysfunction, marked by impaired oxidative phosphorylation, excessive oxygen species (ROS) production, and defective quality control, disrupts these processes and causes cellular and organ damage