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IGF-1 regulation of oxidative stress in Alzheimers disease (AD) and related dementias Moreover, intriguing parallels have emerged between OS and the accumulation of lipid peroxidation products, along with altered expression patterns of insulin/IGF signaling and receptors in postmortem human brain tissue from cases of frontotemporal lobe dementia [42]

SiNPs are nanosized particles of silicon dioxide (SiO 2 ) that have unique physical and chemical properties, such as high surface area, high reactivity, high stability, and easy penetration into plant cells 10

Fig.2 ADCs containing a disulfide linker