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When the antioxidant system of GPX4 is damaged, PUFA-PL oxidation leads to iron-dependent accumulation of PLOOH, which disrupts the integrity of the lipid bilayer and, subsequently, the cell's defense ability against LPO weakens, resulting in uncontrolled LPO

Recent advances in gut microbiome modulation: effect of probiotics, prebiotics, synbiotics, and postbiotics in inflammatory bowel disease prevention and treatment

Several factors can reduce the glutathione level in your body such as stress, poor diet, environmental toxins, for instance, pollution

Link SL, Rampon G, Osmon S, Scalzo AJ, Rumack BH

E.Geu-FloresF.HalkierB

Chem 9 , 20162038 (2023)