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Gong et al (225) found that Erastin promotes the differentiation of fibroblasts into myofibroblasts by increasing lipid peroxidation and inhibiting GPx4 expression, while Fer-1 inhibits ferroptosis and fibrosis by suppressing lipid peroxidation and enhancing GPx4 expression

In studies using dehydroepiandrosterone (DHEA), an inhibitor of G6PD (that is also an adrenal steroid), loss of G6PD function has been suggested to prevent cancer progression 20,21