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As expected, the GSH levels within the mitochondria decreased (Fig

Kumagai T, Matsukawa N, Kaneko Y, Kusumi Y, Mitsumata M, Uchida K

Thus, it is not surprising that GSH (or the [GSH]/[GSSG] ratio) plays a key role in many diseases including cancer, inflammation, Alzheimer's disease, Parkinson's disease, sickle cell anemia, liver disease, cystic fibrosis, AIDS, heart attack, stroke, and diabetes [4, 6] as well as in aging [79]

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Among these subtypes, HGSOC is the most prevalent in clinical settings, accounting for 70-80% of OC-related deaths (53)

Hultqvist M, Olofsson P, Holmberg J, Backstrom BT, Tordsson J, Holmdahl R