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Differences in pigmentation and predisposition to sunburn are the basis for the classification of races (Celtic, Caucasian, and Negroid race) and skin phototypes according to the Fitzpatrick scale (IVI phototype) [67]

Figure 4 The functional coupling between the cerebellum and M1 is particularly relevant for pain modulation, given that M1 stimulation induces analgesic effects in chronic pain conditions

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