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By interacting with the Lys140 residue of NIMA-related kinase 7 (NEK7), A20 and its derivative peptides hinder the NEK7-NLRP3 interaction, suppress macrophage STING signaling and NLRP3-mediated pyroptosis, and thereby effectively relieve auto-DNA-induced AKI [179]

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Biosafety assay of NP4 The biosafety of Ru(II)-OH and NP4 (Ru 800 , 200 L) were evaluated in healthy female BABL/c mice

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Excessive alcohol consumption depletes glutathione stores