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For most midlife women, this is not a primary reason to consider GHK-Cu but it is the biological context that explains why a single small peptide has effects ranging from skin to hair to broader tissue repair

In this process, methionine is formed from homocysteine by methionine synthase, a vitamin B 12 -dependent enzyme

Metabolism does not appear to be altered by chronic exposure, thus dose escalation appears to arise from pharmacodynamic rather than pharmacokinetic tolerance [24]

This is due to a few physiological differences between the sexes

These findings have not been replicated in human trials

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