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More recent trials have associated oral propionyl-L-carnitine supplementation (2 g/day for several months) with improved walking distance and claudication onset time (66, 67), as well as with higher pain-free walking distance and higher ankle-brachial index (a diagnostic measure of peripheral arterial disease) (68)

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As awareness increases, more healthcare practitioners are exploring therapeutic strategies that may support mitochondrial function

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Another study compared the effects of oral and injected L-Carnitine on flap survival in surgical procedures

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