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Nevertheless, the ratio of cGP:IGF-1 influences IGF-1 function possibly through interfering with the binding of IGF-1 to IGFBP-3

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Olivieri G, Brack C, Mller-Spahn F, Sthelin HB, Herrmann M, Renard P, et al

We therefore supplemented His at concentration 5 mM into the growth medium in following flask-scale experiments

S -glutathionylation depicts a regulatory feed forward mechanism whereby GSH, in a form of a protein-mixed disulfide with OTUB1, regulates its own synthesis in an SLC7A11-dependent manner