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178 Overexpression of HSP27 is strongly associated with tumorigenesis, metastasis, and poor prognosis in various cancers, including head and neck squamous cell carcinoma, pediatric acute myeloid leukemia, breast cancer, and colorectal cancer

The peak fiber CSA in treated mice was maintained at approximately 2000 m, a value comparable to that in WT mice (~2500 m) and substantially greater than the reduced range (5001500 m) observed in untreated ALS mice (Fig

Thus, to treat bacterial and fungal infections, it is indispensable to recognize novel antimicrobial agents

J Mater Chem B 3:68566870

Senolytic agents include natural compounds such as quercetin 13 or fisetin 14 , -galactosidase-activated nanoparticles and prodrugs 15,16,17 or compounds that target different vulnerabilities of senescent cells, such as HSP90 inhibitors 18 , cardiac glycosides 19,20 or NMT inhibitors 21