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Maruyama K, S Eshak E, Kinuta M, et al. Association between vitamin B group supplementation with changes in % flow-mediated dilatation and plasma homocysteine levels: a randomized controlled trial. J Clin Biochem Nutr. 2019;64(3):243-249. doi:10.3164/jcbn.17-56

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However, despite early recruitment of highly mutated B-cell clones reflecting cross-reactive hCoV memory, these responses are mostly nonneutralizing [92, 94,95,96,97] and decline between three and six months after infection, whereas de novo-generated B-cell responses expand and largely contribute to the nAb response [94]