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[DOI] [PMC free article] [PubMed] [Google Scholar] Barnes I., Solignac G., Mellouki A., Becker K

We think that while it is clear that different endpoints may yield quite different results, the human MOE for cannabis based on the endpoint psychotropic effects can be seen as general validation of the MOE concept, because the resulting values below 1 are expected as the psychotropic effect is the desired endpoint (and hence the psychotropic threshold dose is exceeded by drug users)

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Two scales were created based on the outcomes: pros and cons of smoking

The differential effect of cigarette smoke on the growth of bacteria found in humans

Strong roasted notes are added and well the used Havanna aromas of wood and leather, which offers a not necessarily subtle, but very varied smoking experience