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PMID: 6 FerlayJPartenskyCBrayF

Altered redox regulation and S-glutathionylation of BiP contribute to bortezomib resistance in multiple myeloma

heating methods include laser, ultrasound, radiofrequency, and microwave radiation (ACS 2013b

However, these concentrations may be sufficient to induce relevant biological effects, especially when considering its accumulation in cellular compartments such as mitochondria

Here we present seven crystal structures of the enzyme in complex with substrate (glutathione) and two inhibitors (S-hexyl glutathione and gamma-glutamyl- (S-benzyl)cysteinyl-D-phenylglycine)