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Finally, dihydrolipoamide dehydrogenase activity in the glycine cleavage system (L protein) and in the -ketoacid dehydrogenase complexes (protein E3) catalyzes the conversion of the dihydrolipoyl moiety (reduced form) to the lipoyl moiety (oxidized form)

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[24] revealed neuroprotection and neuroregeneration by GPE in which the tripeptide enhanced proliferation and migration in mouse neural stem cells (NSCs) following injury involving 13.5 Days post-conception (dpc) mouse embryos

Laboratory investigations suggest that Ac-SDKP promotes angiogenesis, supports vascular repair, and may protect bone marrow cells from toxic stressors such as chemotherapy agents

The peptide's anti-inflammatory effects may complement NSAIDs or other anti-inflammatory agents, though combined effects require clinical evaluation