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Increased MPO blood levels also associate with increased risk for atherosclerosis (274-277) and polymorphisms in the MPO gene that lower MPO activity reduce the risk for atherosclerosis (278,279)

372,373 In neoadjuvant endocrine therapy of HR+/HER2 breast cancer, achieving pCR is not the primary goal, therefore studies such as NeoMONARCH and PALLET focus on changes in Ki67 levels and complete cell cycle arrest with the addition of CDK4/6 inhibitors

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Free Radic Biol Med 15(6):645651 Lewenza S, Gardy JL, Brinkman FS, Hancock RE (2005) Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen

High expression on multiple myeloma (MM) cells and limited expression on normal cells makes CD38 an ideal target for the treatment of MM patients

On the other hand, experimental studies are necessary to understand the exact mechanisms underlying the adverse effects of pyocyanin