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doi: 10.1371/journal.pone.0095268

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More recently, RNA-seq analysis was used to investigate gene expression in iPSCs-neurons from donors with SCZ and autism spectrum disorders due to 22q11.2, showing downregulation of 753 genes, the majority being included in apoptosis, cell cycle, cell survival and MAPK signaling Gene Ontology, with a particular attention to the sub-network modulated by PRODH (Lin et al., 2016b)