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Recently, it was concluded that A peptides associated with AD form a unique Cu(A) complex to which PBT2 cannot effectively bind

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reported that light-responsive Doxorubicin (DOX) -loaded nanocapsules showed considerable anticancer action in vivo as well as in vitro

For instance, AZD1775 (adavosertib) monotherapy has demonstrated antitumor activity in treatment-refractory solid tumors with CCNE1 amplification, with particularly encouraging responses observed in epithelial ovarian cancer in a phase II trial 198 (NCT03253679, ClinicalTrials.gov, 2023)