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Brosch, M

One approach that has been reported consists of the use of pharmaceutical compounds with chaperone-like properties such as taurine-conjugated ursodeoxycholic acid derivative (TUDCA) and 4-phenylbutyric acid (PBA) that have the ability the improve the ER folding capacity ( Besides, pancreatic -cell ER stress is reported to be directly involved in the pathogeny of some forms of monogenic diabetes ( MODY-1 is caused by a point mutation of the hepatocyte nuclear factor 4 (HNF4) gene

Functional assays, such as parthenogenetic activation and MMP measurement, offered insight into the biological quality of oocytes

Lund, A., Knop, F

Biomed Pharmacother 168:115716 Storgaard L et al (2021) Glaucoma clinical research: trends in treatment strategies and drug development

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