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The FDA requires extensive animal testing before human trials specifically because dangerous substances generally produce detectable harm in animal models

Those getting prescribed injections from their doctor are likely to only need them once every few months at a very high dosage which is not meant to be used weekly or daily

Subcutaneous use is uncommon and dose-limited

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Storage and stability after reconstitution Reconstituted retatrutide is a protein in solution, and like all proteins in solution, it degrades over time