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Lactate has been demonstrated to trigger macrophage polarization as well as promote tissue regeneration [103]

These findings not only expand the repertoire of cancer-associated splicing factors but also highlight novel molecular vulnerabilities for spliceosome-targeted interventions

J Cell Mol Med 12: 987994, 2008

Brain 125:15101521 Desaphy JF, Pierno S, Liantonio A, Giannuzzi V, Digennaro C, Dinardo MM et al (2010) Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles

Additionally, TRAF6 can activate mitogen-activated protein kinases of the MaPK family

*Correspondence: Chamroon Laosinwattana, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers