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Identifying compound efficacy targets in phenotypic drug discovery

Methotrexate-induced liver injury is associated with oxidative stress, impaired mitochondrial respiration, and endoplasmic reticulum stress in vitro

After 2 h of APAP injection, APAP_Leu group was gavaged with leucine (1.5% w/v, 10ml/kg) and APAP group was given an equivalent volume of PBS

To do this she was able to draw on a collaboration with scientists from Millipore Corporation, a company located near Boston Massachusetts

Zhang X, Sui S, Wang L, Li H, Zhang L, Xu S

These disrupted cycles may resume when disease activity subsides or if the follicle manages to remain in the anagen phase for a prolonged duration (Fig