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Description

Van Oostrom, R

Murao, Y

Local drug administration represents a form of passive targeting in which anticancer agents are directly applied to the oral cavity

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Only recently, attention has been paid to the study of metal ions and inorganic small molecules to intervene in the mechanism of physiopathological processes, with special attention to the differences between inorganic and organic drugs in terms of absorption, transit, distribution, metabolism, toxicology, and pharmacological effects (Meiling et al., 2013)