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MRP7 Long MRP Role a lipophilic anion transporter, involved in phase III (cellular extrusion) of detoxification, does not directly transport GSH

The initial phases of SARS-CoV-1 replication involves translocation of the N protein to the host nucleolus

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doi: 10.1007/s00277-020-03916-8 101 WenQLiuJKangRZhouBTangD

2 Mitochondrial dysfunction in ASD From a clinical point of view, mitochondrial dysfunction in ASD may be the cause of seizures, motor delay, fatigue and neurodevelopmental regression ( Mitochondrial dysfunction itself can be categorized into two types: the first type represents a mutation of a gene which is associated with the ATP-generating pathway, while the second one is related to various abnormalities such as genetic, biochemic or metabolic, that may weaken the ability of the mitochondria to produce ATP ( A central mechanism often implicated is the dysfunction of Electron Transport Chain (ETC), which plays a crucial role in ATP production

PLGA-based nanoparticles can cross the BBB by active processes namely receptor-mediated transcytosis (RMT) and carrier-mediated transport (CMT)