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it stabilises the cellular environment by acting as a soothing agent

These neurotransmitters play essential roles in mood regulation, and their dysregulation is implicated in the development of depressive symptoms

Autoimmune disease represents a failure of both systems

Numerous pharmacological, behavioral, and imaging studies have demonstrated the imbalance in excitatory and inhibitory neurotransmitters, thus revealing the involvement of the glutamatergic system in ASD pathology

Additionally, probiotics enhance the glucose-lowering/hypoglycemic effects of metformin by facilitating butyrate production, reflected by reductions in fasting blood glucose, insulin resistance, and fibronectin levels [148]