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Indeed, animal model studies involving transgenic mice indicated hippocampal depletion of GSH precedes the elevation of A42/A40 ratio and the aggregation of the tau protein [32, 33]

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[DOI] [PMC free article] [PubMed] [Google Scholar] Shults CW, Oakes D, Kieburtz K, Beal MF, Haas R, Plumb S, Juncos JL, Nutt J, Shoulson I, Carter J, et al

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Epinephrine is the first-line treatment for anaphylaxis and acts through multiple adrenergic receptors to rapidly reverse life-threatening cardiopulmonary and systemic manifestations