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Bmc Ophthalmol

Apart from IL-17, researchers also found that circulating IL-6 could act on the main cell adhesion component of endothelial cells, tight junction protein claudin5 (Cldn5), which alters BBB permeability (61)

Blue: Bansal and colleagues

Acid retention during kidney failure induces endothelin and aldosterone production which lead to progressive GFR decline, a situation ameliorated by alkali diet