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DISCUSSION Many studies conducted in recent years have reported various biological effects, spanning epidemiological and clinical investigations in humans, as well as experimental research involving rodents, flies, and cell cultures exposed to phone radiation[46]

This mechanism of action blocks the expression of pro-inflammatory cytokines such as TNF-, IL-6, COX-2, AP-1/HO-1, and iNOS, thereby reducing the inflammatory response and tissue damage (Zhou et al., 2021)

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Furthermore, the reversal of SidEs-induced ubiquitination by DupA and DupB produces phosphoribosyl ubiquitin (PR-Ub) 9,10