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Pathogenic microbes and pro-inflammatory cytokines originating from the gut further exacerbate CNS disorders, increasing the likelihood of developing chronic neurodegenerative diseases (Wu et al., 2021

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In high-severity patients after liver transplantation, gut barrier function is more persistently and severely impaired, with a higher proportion of pathogens like Escherichia coli and Shigella flexneri in their feces, while butyrate producers like Roseburia intestinalis are positively correlated with albumin levels, suggesting an interconnection between dysbiosis and barrier damage

No significant impact of age, gender or treatment on the neutralizing titers was observed in this limited cohort

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