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The potential role of the ubiquitin-proteasome system (UPS) in the regulation of glutamine metabolism in tumor cells remains to be fully elucidated

Consequently, the exact role of SHBG in neurodegenerative diseases and its clinical translational value require further validation through rigorously designed studies

Uffelmann, E

For instance, the genetically engineered probiotic strain Escherichia coli Nissle 1917 colonizes tumor sites and continuously converts ammonia metabolites into L-arginine

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IFN also induces an increase in barrier permeability through the reduction of ZO-1 and occludin expression in an adenosine monophosphate-activated protein kinase (AMPK)-dependent pathway, irrespective of the cellular energy levels 62