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It should not be expected to reverse severe osteoarthritis, regrow advanced cartilage loss, correct major joint deformity, heal a complete tendon rupture without appropriate orthopedic management, or replace surgery when surgery is clearly indicated

Epitalons appeal lies in its unusually broad mechanistic reach: it can activate telomerase and support telomere maintenance in human cells [12,13,14, 15], modulate gene expression epigenetically by influencing chromatin accessibility and promoter interactions [4], enhance tissue repair in disease contexts such as diabetic retinopathy by reducing oxidative stress and EMT while improving wound healing in retinal cells [16], bolster redox homeostasis by upregulating endogenous antioxidant defenses and lowering DNA-damage markers [1], rebalance immune tone via IL-2 upregulation [17] and shifts in CD4+/CD8+ profiles [18], and even reset circadian biology by tuning core clock genes and melatonin dynamics [19, 20]

Physicians cannot prescribe it, and pharmacies cannot dispense it as a medication

Sometimes reading instructions isn't the same as seeing them

Ensure your expectations align with the actual scientific literature, not marketing copy

Expansion of the quantity of existing technology in the absence of a new innovative use or need