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Therefore, future research urgently needs to evaluate the efficacy of compound 25L and its analogs in diabetic animal models, focusing on resolving potential off-target effects and long-term toxicological issues to advance this promising target toward clinical translation

First, the association of ferroptosis with multiple psychiatric disorders, which already exist as comorbidities in BD, supports a potential intersection of their mechanisms

Cytotoxicity of the novel glutathione-activated thiopurine prodrugs cis -AVTP [ cis -6-(2-acetylvinylthio)purine] and trans-AVTG [trans-6-(2-acetylvinylthio)guanine] results from the National Cancer Institutes anticancer drug screen

Mol Cancer Ther (2015) 14:192838

To guide treatment decisions, the National Rosacea Society (NRS) Expert Committee classified the condition into four subtypes and one variant

Drug Test Anal 2012