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Secondly, several cell- and growth factor-based regenerative treatment strategies have been tested in vitro and in vivo in animal models with experimentally induced IVD degeneration

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Hopefully this will pass as treatment progresses

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IGF1-LR3, a modified version of insulin-like growth factor-1, has a longer half-life than standard IGF-1 because it does not bind to IGF-1 binding proteins well