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However, it is unclear whether the immunological mechanisms behind hyperinflammation of MIS-C are the same as that in adults with COVID-19

J Neurosci 32(41):1431814330

Robbins TW

If so, the CK1-mediated phosphorylation of Axin S359 alone would initiate or, in conjunction with the phosphorylation of Axin T384, downregulate Wnt signaling providing a context-dependent phosphorylation switch that would be interesting to test in future studies