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Dickerson F, Stallings C, Origoni A, Vaughan C, Khushalani S, Yolken R

Curr Opin Genet Dev 17, 4551 (2007)

Still, theres promising evidence that the supplement may change the brain and nervous system in a way that helps lessen symptoms of: Major depressive disorder Schizophrenia Bipolar disorder Posttraumatic stress disorder (PTSD) Obsessive-compulsive disorder Trichotillomania (hair pulling) Substance use disorders Some studies show that the supplement may help ease symptoms of withdrawal, including a strong urge or craving to take drugs

Mechanistically, the natural secondary metabolite trichothecin significantly increased the expression of RIPK3

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11451-1-AP), HMOX1 (Proteintech, cat