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Indeed, Iodine deficiency impairs normal thyroid function and is associated with a spectrum of thyroid disorders, the severity of which varies depending on the degree of deficit and the individuals age [17, 18]

Niacin in the central nervous system: an update of biological aspects and clinical applications

This depletion leads to a state of cellular energy failure

NK cells are also dysfunctional in contexts of obesity and T2DM, displaying increased proliferation rates and IFN secretion, and impaired degranulation, respectively (246)

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