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However, the efficacy of small molecule inhibitors targeting NNMT remains uncertain due to their lack of selectivity and low metabolic stability (Iyamu and Huang, 2021)

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Research indicates that NNMT expression correlates positively with insulin resistance, with plasma levels of the NNMT product 1-methylnicotinamide associated with increased body mass index and metabolic dysfunction

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Butkowski et al

B12 plays a key role in metabolism, supporting healthy weight management as part of your wellness routine