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Barth, C

While p53 has been classically recognized to impede cancer development by mediating cell cycle arrest, apoptosis, and senescence, new evidence suggests that p53 can induce ferroptosis in cancer cells by regulating metabolic activities

Methods: A total of mice were divided into 6 groups: (i) normal control (ii) diabetic control, (iii) normal + 15 (mol sinigrin/kg BW for all), (iv) diabetes + 15, (v) normal + 30 and (vi) diabetes + 30