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AST/Bex also upregulated the expression of ABCA1, LRP1, and/or APOA-I, thereby facilitating cholesterol efflux partially through PPAR/RXR activation, and downregulated cholesterol biosynthesis and esterification

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Habib E, Linher-Melville K, Lin H-X, Singh G

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Associations between placental CpG methylation of metastable epialleles and childhood body mass index across ages one, two and ten in the extremely low gestational age newborns (ELGAN) cohort epigenetics

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Nevertheless, by pooling the data, we were able to construct an accurate model based on, respectively, more than 600 and more than 300 PK and PD data points

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In thalassemia, unstable globin chains and excess free iron generate reactive oxygen species, which damage red blood cell membranes and shorten their lifespan

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Thirdly, the current study focused on patients with MoCA scores below 26, and future research would benefit from including SCZ patients with minimal cognitive deficits (MoCA 2730) to provide a more comprehensive understanding of the relationship between ferroptosis markers and cognitive function in SCZ

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