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Optimal results typically appear after 3-6 months of regular application

Empirical data suggests that certain nations' medicinal plants might harbour toxic fungal infections ( Aspergillus, Fusarium ) [101]

Furthermore, it is important to note that the olfactory epithelium in rats and mice is about 40%50% of the total nasal surface

A prospective trial of vitamin C in ALS indicated that the presence of ascorbate will cause the progress of the disease and the use of ascorbate could have unfavorable effects in ALS patients (62)