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For instance, 95.1% of patients on the 8-week schedule lost fewer than 15 ETDRS letters at week 52

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Can Res 55:47714775 Mulcahy RT, Gipp JJ (1995) Identification of a putative antioxidant response element in the 5'-flanking region of the human gamma-glutamylcysteine synthetase heavy subunit gene

Many MCAS patients have impaired pathways for converting glutamate into calming GABA, leading to "glutamate excitotoxicity"which can manifest as severe anxiety, insomnia, heart palpitations, and brain fog