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Collectively, these findings demonstrate forskolins capacity to address multiple pathological features of AD, including amyloid plaque accumulation, tau hyperphosphorylation, oxidative stress, neuroinflammation, and synaptic dysfunction

Western blot analysis validated the finding showing that SIRT4 reduced -SMA and Col1a1 expression in LX-2 cells compared with the control group (Fig

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There is growing evidence that various neurodegenerative diseases, including Parkinsons disease, stroke, Huntingtons disease, and traumatic brain injury, are associated with ferroptosis (98, 99)

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