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MOMP is regulated by members of the B-cell lymphoma 2 (Bcl-2) family of proteins, which include both anti-apoptotic and pro-apoptotic proteins

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The compound was also investigated as PL14736 in early-phase IBD clinical work, as described in a 2008 paper by Klicek and colleagues in Journal of Pharmacological Sciences , though that clinical program was never completed or approved

Fatigue and Headaches : A few individuals report feeling tired or experiencing headaches after receiving the injections, although these symptoms are typically transient

PD and several related neurodegenerative disorders can also been considered as proteinopathies, in which the core neurodegeneration of nigrostriatal dopaminergic neurons in PD is also associated with a more widespread cellular deposition of alpha-synuclein 8