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Description

(127) published in Cell Host Microbe in 2023 identified two distinct gut microbial pathways involved in PAGln production

The chemical reactivity of these molecules varies, and their targets in a physiological environment are determined by kinetic factors

M.MarshallE

Spermidine trihydrochloride was non-genotoxic in the in vitro assays, and no adverse effects were reported in the 90-day oral (dietary) toxicity study up to the highest dose tested, which was 728 mg/kg bw/day for males and 829 mg/kg bw/day for female rats 132