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An explorative principal component analysis showed distinct protein expression patterns by cohort and visit, with Durban participants clustering separately from IAVI participants (Fig

Moreover, supplementation of D-mannose in vitro can induce metabolic remodeling in T cells, enhance O-GlcNAc transferase (OGT)-mediated O-GlcNAcylation of -catenin, and ultimately maintain their stemness characteristics and anti-tumor activity [370]