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Age Older people and people having chronic conditions like diabetes, COPD, Asthma, etc have decreased levels of glutathione

Rats were assigned to experimental groups randomly at the beginning of adolescent treatment

They cause oxidative damage to blood vessels, air sacs, and heart muscle

10.1371/journal.pone.0152236 99 YuK.GengX.ChenM.ZhangJ.WangB.IlicK.et al (2014)

As discussed previously, ITCs might either directly affect the folding of proteins or might through the depletion of GSH affect the oxidizing status of the ER and hence the disulphide bond formation involved in protein folding

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