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The limiting factors include: (1) the inability of GSH to cross the cell membrane via direct absorption

leading to a potential biochemical riboflavin deficiency worldwide ( As a matter of fact, neural tissue has a higher susceptibility to oxidative stress

Cognitive impairment and mortality in a cohort of elderly people

Metallomics 9 (10), 14391446

40 The Nrf2/ARE pathway, by inducing antioxidant and anti-inflammatory responses, contributes significantly to the alleviation of oxidative stress and inflammation in the gut, thus playing a protective role in conditions like IBD

The extract of FE inhibited hemolysis in a concentration-dependent manner, suggesting its involvement in stabilizing the erythrocyte membrane